After the war, the Museum suffered from the cultural backwardness and international isolation characterised by Franco's dictatorship and for a time it was renamed the National Museum of Religious Sculpture.
In the sixties, an effort was made to enhance the quality of its services; collections and publications were presented in a better way, and spaces were improved. In 1968, the collection of paintings was exhibited in the deconsecrated Church of the Passion.
The uniqueness of the College and the expressiveness of its sculptures attracted great artists. Orson Welles filmed the magnificent masquerade ball for the film Mister Arkadin, at the College, and José Val del Omar, filmed the groundbreaking documentary Fuego en Castilla there.