The synagogue was built in XIV century by Samuel ha-Levi, the treasurer of King Pedro I of Castille.
The synagogue shows one of the most beautiful examples of mudejar style in Hispanic-Jewish legacy. The walls are made of plaster works and the beautiness of the wooden roof are one of the special details that higlights this building.
Its historical evolution like building has turned this space into a catholic church, Archive of a Military Order, and finally Sephardic Museum.
After Jewish Expulsion in1492, Catholic King exchanged this building with Calatrava Order Knights, who transformed the space into a church, and a hospital was built here. After XVI it was only used for religious services like Transito church until XIX Century. Oficially declared like National Monument the 1st of May in 1877, there were taken into account the first restoration measures.
The synagogue is considered the most important museum piece, as it contains one the main museum´s message.